In an era of ever-increasing healthcare costs, knowledge of cost effectiveness is critical for US physicians, policymakers, and payers alike. Results from a cost-effectiveness study undertaken by investigators from PHAR, LLC and Bristol-Myers Squibb was presented at the 10th International Congress on Drug Therapy in HIV Infection. The model found that patients using atazanavir with ritonavir experience AIDS diagnoses, opportunistic infections, coronary heart disease events, and diarrhea episodes less often than patients using lopinavir in combination with ritonavir.

Two posters detailing findings from a systematic literature review were presented at the International Society for Pharmacoeconomics 14th Annual European Congress. The systematic review examined the impact of skeletal-related events on pain, quality of life, morbidity, survival, and cost in patients with prostate and breast cancer. The report was created by PHAR, LLC researchers in collaboration with researchers at Bristol-Myers Squibb.

PHAR, LLC presented research on schizophrenia management at the American Psychiatric Association’s 2010 Institute on Psychiatric Services. PHAR investigators conducted a retrospective cohort study of antipsychotic therapies, and findings from this study confirmed that adherence to antipsychotic treatment is an important determinant of health service use in general and hospitalization in particular. Outcomes may be improved in patients by choosing medications whose effect is less likely to be reduced by imperfect adherence-specifically those with longer half-lives.

PHAR, LLC presented findings from an economic impact study on the use of alvimopan at the American College of Surgeons 96th Annual Clinical Congress. Results suggested that, along with other initiatives to improve quality and reduce costs of surgical care, alvimopan should be considered for use in the management of patients who undergo segmental bowel resection. PHAR investigators produced the study in collaboration with researchers at GlaxoSmithKline, UCLA Center for Surgical Outcomes and Quality, University of Colorado School of Pharmacy, EnPharma Consulting, and Adolor Corporation.