PHAR’s Michael S. Broder, MD, MSHS, Sarah N. Gibbs, MPH, and Irina Yermilov, MD, MPH published an article describing how they adapted the RAND/UCLA modified Delphi panel method, which typically relies on an in-person meeting, during the COVID-19 pandemic. This virtual method can be a cost-effective and efficient alternative for researchers and clinicians. Their work was previously presented as a poster at ISPOR’s annual meeting in May 2022, which can be viewed here. The article can be read on the PHAR publications page and in the Journal of Healthcare Leadership.
Archives for 2022
In collaboration with Pharmaceutical Research and Manufacturers of America, PHAR developed an issue brief discussing how cost-effectiveness analyses can perpetuate health inequities. Cost-effectiveness analyses are commonly used to compare interventions, but fail to account for a diverse patient population. Read the issue brief here.
PHAR’s President, Michael S. Broder, MD, MSHS, mediated a webinar discussion today with panelists Eric Benchimol, MD, The Hospital for Sick Children in Toronto, Karina Raimundo, MS, HEOR Director at Genentech, and Anil Vachani, MD, MS, of Penn Medicine on best practices surrounding ICD code validation in secondary data research using Medicare or commercial claims. Recently, Dr. Broder wrote on the importance of algorithm validation in claims analyses, which was published on HealthEconomics.com. The webinar attracted more than 80 professionals and academics in pharmacy, medical statistics, healthcare, and health economics insights. The recording of the webinar is available on-demand on InsideScientific.com, and the Q&A report available for download here.
Two studies conducted by PHAR were presented as posters at AMCP 2022. The first study, in partnership with Sunovion Pharmaceuticals, developed clinical consensus on the use of on-demand treatments for Parkinson’s disease (PD) by convening experts to participate in a RAND/UCLA modified Delphi panel. In most evaluated scenarios, panelists agreed on-demand treatment is appropriate for PD patients with OFF episodes, especially for patients experiencing a significant functional impact. The second study, in collaboration with Genentech, presented the interim results of their claims-based algorithm used to identify patients with neuromyelitis optica spectrum disorder (NMOSD). The algorithm helps distinguish patients with NMOSD from patients with multiple sclerosis and other central nervous system inflammatory disorders, allowing researchers and clinicians to better estimate NMOSD burden. The posters can be viewed on the PHAR publications page and abstracts printed in the March supplement issue of the Journal of Managed Care + Specialty Pharmacy.
PHAR, in collaboration with Genentech, presented the interim results of their claims-based algorithm used to identify patients with neuromyelitis optica spectrum disorder (NMOSD) at ACTRIMS 2022. The algorithm helps distinguish patients with NMOSD from patients with multiple sclerosis and other central nervous system inflammatory disorders, allowing researchers and clinicians to better estimate NMOSD burden. The poster can be viewed on the PHAR publications page and the abstract published in the May 2022 supplement of Multiple Sclerosis Journal Online.
Research conducted by PHAR and supported by Amgen was published in the February 2022 issue of Current Medical Research and Opinion. PHAR’s Jesse Ortendahl, Eunice Chang, PhD, Amanda Harmon, and Michael S. Broder, MD, MSHS analyzed disease burden across 8 different conditions using QALY assessments and other measurement instruments, uncovering possible biases and deficits that may result from the current precedent of using QALYs to measure disease impact in economic evaluations. The manuscript can be found on the PHAR publications page.