Physician experts from 10 regionally based academic practices in the US formed an expert panel with the purpose of developing a consensus on the appropriateness of medical therapies for grade 1-2 unresectable neuroendocrine tumors of the pancreas (PNETs). The panel was facilitated using the RAND/UCLA modified Delphi process, a systematic method for group decision making. The panel statements agreed with-and increased the detail of-previously published PNET guidelines. The full results of the expert panel were presented at a poster session of the 94th Annual Meeting & Expo of ENDO in Houston, Texas.